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BIOT9004 - Systems Biology

Title:Systems Biology
Long Title:Systems Biology
Module Code:BIOT9004
Credits: 10
NFQ Level:Expert
Field of Study: Biotechnology
Valid From: Semester 1 - 2011/12 ( September 2011 )
Module Delivered in 1 programme(s)
Module Coordinator: BRENDAN O CONNELL
Module Author: HUGH MC GLYNN
Module Description: This module provides a comprehensive overview of Systems Biology – allowing students to apply interdisciplinary analysis of complex biological networks across multiple hierarchical levels in situ.
Learning Outcomes
On successful completion of this module the learner will be able to:
LO1 Apply the concept of systems biology and evaluate its contribution to modern molecular biology.
LO2 Analyse gene mining in the context of large scale DNA sequencing from a number of different environments.
LO3 Interpret how gene array technology can be used to identify when and to what extent genes are activated.
LO4 Critically evaluate the techniques used for studying protein structure and function and outline how protein interactions can be elucidated.
LO5 Critically appraise how metabolic profiling can lead to a greater understanding of physiological processes.
LO6 Demonstrate an ability to understand and critically evaluate the current literature relating to different aspects of systems biology.
Pre-requisite learning
Module Recommendations
This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named CIT module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
No recommendations listed
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed

This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.

No requirements listed
No Co Requisites listed

Module Content & Assessment

Indicative Content
Systems Biology Overview
An introduction to the concept of systems biology and its role in integrating transcriptomic, proteomic and metabolomic information to give a more complete picture of living organisms.
Genomics and Metagenomics
A comprehensive overview of large scale DNA sequencing strategies; form the human genome project to the metagenomics approach to sequencing the entire genetic complement of different environments.
A detailed analysis of the complete set of RNA transcripts (expressed DNA) produced by the genome at a particular time or in response to external stimuli.
Analyses of the entire protein complement of an organism, with particular emphasis on structure, function and global protein interactions.
A systematic study of how metabolic profiling can give an instantaneous snapshot of the physiology of an organism.
Assessment Breakdown%
Course Work30.00%
End of Module Formal Examination70.00%
Course Work
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Other Moderated online discussion of the major 'omics' technologies described in lectures and analysis of their impact on modern society 1,6 30.0 Every Week
End of Module Formal Examination
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Formal Exam End-of-Semester Final Examination 1,2,3,4,5,6 70.0 End-of-Semester
Reassessment Requirement
Repeat examination
Reassessment of this module will consist of a repeat examination. It is possible that there will also be a requirement to be reassessed in a coursework element.

The institute reserves the right to alter the nature and timings of assessment


Module Workload

Workload: Full Time
Workload Type Workload Description Hours Frequency Average Weekly Learner Workload
Lecture face to face and blended learning 3.0 Every Week 3.00
Lecturer-Supervised Learning (Contact) presentations and online discussion forum 3.0 Every Week 3.00
Independent & Directed Learning (Non-contact) critical evaluation of the prescribed literature 8.0 Every Week 8.00
Total Hours 14.00
Total Weekly Learner Workload 14.00
Total Weekly Contact Hours 6.00
This module has no Part Time workload.

Module Resources

Recommended Book Resources
  • Arthur M. Lesk, Introduction to genomics [ISBN: 978 0199296958]
This module does not have any article/paper resources
This module does not have any other resources

Module Delivered in

Programme Code Programme Semester Delivery
CR_SCMPB_9 Master of Science in Computational Biology 2 Elective

Cork Institute of Technology
Rossa Avenue, Bishopstown, Cork

Tel: 021-4326100     Fax: 021-4545343
Email: help@cit.edu.ie