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BIOT6015 - Bioprocess Eng Principles

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Title:Bioprocess Eng Principles
Long Title:Bioprocess Engineering Principles
Module Code:BIOT6015
 
Duration:1 Semester
Credits: 5
NFQ Level:Fundamental
Field of Study: Biotechnology
Valid From: Semester 2 - 2019/20 ( January 2020 )
Module Delivered in 2 programme(s)
Module Coordinator: NIALL MORRIS
Module Author: IAN O SULLIVAN
Module Description: This module will provide an insight into the role of the Chemical & Bio-pharmaceutical Engineer in the manufacture of biotechnological products. It will also introduce the student to quantitative aspects of bio-process engineering such as bio-stoichiometry, material and energy balances on biological systems, modelling and sterilization of batch and continuous microbial and enzymatic bioreactors.
Learning Outcomes
On successful completion of this module the learner will be able to:
LO1 Identify the safety, moral and ethical issues associated with industrial bio-processing.
LO2 Discuss the differences between the processes for producing high value/low volume and low value/high volume biotechnological products.
LO3 Calculate bio-stoichiometric coefficients and heats of reactions for biological conversions.
LO4 Model microbial growth, substrate consumption, product formation and thermal deactivation in batch and continuous bioreactor systems.
LO5 Carry out and report on practical experiments relating to concepts covered in class.
Pre-requisite learning
Module Recommendations
This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named CIT module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements

This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.

None
 

Module Content & Assessment

Indicative Content
The colours of biotechnology
Social, moral and ethical considerations. GM foods. Applications of human and animal genetic research. Regulatory requirements. Euro-barometers. Genetic engineering safety. Bio-hazards. Wastewater characterisation and treatment, anaerobic digestion and bio-remediation (Green). Production of compounds from marine microbes and bio-fuels from algae (Blue). Manufacture of bio-pharmaceutical products and production methods (Red). First and Second generation bio-fuel production, bio-refineries, antibiotic and beer production (White).
Bio-ethanol production processes
Quality, raw materials, mashing, wort separation, wort boiling, fermentation and conditioning of beer. Raw material preparation fermentation and process integration for bio-ethanol production.
Bioreactor modelling
Modelling and kinetics of micro-organism growth and thermal deactivation in batch and continuous systems.
Bioreactor Design
Heat of reaction for processes with biomass production. Stoichiometry of cell growth and product formation. Key features and functions of bioreactors. Bioreactor feeding regimes and productivity. Material balances on batch, continuous and continuous systems with recycle.
Laboratory Programme
Green Biotechnology: Nitrates, Phosphates, COD, instrument calibration and use. Brewing Studies: Factors effecting cell growth, determination of biomass, substrate and product concentrations during the brewing process. Biopharmaceutical Processing: Chromatographic separation of proteins. Laboratory Skills: Pipetting.
Assessment Breakdown%
Course Work100.00%
Course Work
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Essay Consideration of a current topic in industrial bio-processing. 1,2 20.0 Week 6
Practical/Skills Evaluation Completion of water analysis, laboratory skills and brewing studies worksheets 2,3,4,5 40.0 Every Week
Open-book Examination Bioreactor system modelling and material and energy balances 3,4 40.0 Week 13
No End of Module Formal Examination
Reassessment Requirement
Coursework Only
This module is reassessed solely on the basis of re-submitted coursework. There is no repeat written examination.

The institute reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Workload Description Hours Frequency Average Weekly Learner Workload
Lecture Classroom Instruction 2.0 Every Week 2.00
Lab Practicals 2.0 Every Week 2.00
Independent & Directed Learning (Non-contact) Student Study 3.0 Every Week 3.00
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
Workload: Part Time
Workload Type Workload Description Hours Frequency Average Weekly Learner Workload
Lecture Classroom Instruction 2.0 Every Week 2.00
Lab Practicals 2.0 Every Week 2.00
Independent & Directed Learning (Non-contact) Student Study 3.0 Every Week 3.00
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
 

Module Resources

Recommended Book Resources
  • Pauline M. Doran 2012, Bioprocess Engineering Principles, 2nd Ed. [ISBN: 978-0122208515]
  • Matthew Farber and Roger Barth 2019, Mastering Brewing Science, 1st Ed., Wiley-Blackwell [ISBN: 9781119456056]
Supplementary Book Resources
  • Michael L. Shuler, Fikret Kargi. 2003, Bioprocess Engineering, 2nd Ed. [ISBN: 978-0131228573]
  • edited by Colin Ratledge, Bjorn Kristiansen 2006, Basic Biotechnology, 3rd Ed. [ISBN: 978-0521549585]
This module does not have any article/paper resources
Other Resources
  • Website: The Chemical Engineer
  • Laboratory Manual: CITBioprocess Engineering Laboratory Manual
 

Module Delivered in

Programme Code Programme Semester Delivery
CR_ECPEN_8 Bachelor of Engineering (Honours) in Chemical and Biopharmaceutical Engineering 2 Elective
CR_EOMNI_8 Engineering Common Entry (Level 8) 2 Elective

Cork Institute of Technology
Rossa Avenue, Bishopstown, Cork

Tel: 021-4326100     Fax: 021-4545343
Email: help@cit.edu.ie