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BIOT7001 - Applied Biotechnology

Title:Applied Biotechnology
Long Title:Applied Biotechnology
Module Code:BIOT7001
Duration:1 Semester
Credits: 5
NFQ Level:Intermediate
Field of Study: Biotechnology
Valid From: Semester 1 - 2017/18 ( September 2017 )
Module Delivered in 2 programme(s)
Module Coordinator: Brigid Lucey
Module Author: Rosemary Rea
Module Description: This module will introduce the learner to specialised topics of importance to the biotechnology industry, specifically relating to discovery, types and engineering of bio-molecules.
Learning Outcomes
On successful completion of this module the learner will be able to:
LO1 Describe the potential impact on cells of protein misfolding using specific examples.
LO2 Describe the role of high throughput screening in the drug discovery process.
LO3 Provide an overview of genetic engineering strategies used to generate biopharmaceutical expression systems.
LO4 Provide an overview of different biopharmaceutical therapies.
LO5 Decsribe the role of engineering in generating proteins with altered properties.
LO6 Perform experimental tasks related to drug discovery and development .
Pre-requisite learning
Module Recommendations
This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named CIT module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed

This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.

No requirements listed

Module Content & Assessment

Indicative Content
Protein Folding
Role of the protein quality control system - ubiquitin proteasome system and chaperones. Protein misfolding and disease.
Drug Discovery and Development Process
High throughput screening in drug discovery. Lead compounds. Pre-clinical and clinical trials. Drug approval processes.
Sources of Biopharmaceutical Proteins
Engineering of microbial and mammalian expression systems.
Biopharmaceutical Therapies
Monoclonal antibodies and other proteins. Vaccines. DNA based therapies.
Protein Engineering
An examination of the benefits of protein engineering using insulin as an example.
Laboratory Programme
Conduct relevant laboratory procedures and practical skills.
Assessment Breakdown%
Course Work100.00%
Course Work
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Short Answer Questions Theory based assessment 1,2,3,4,5 60.0 Week 12
Practical/Skills Evaluation Laboratory experiments, presentation and report writing 2,6 40.0 Every Week
No End of Module Formal Examination
Reassessment Requirement
Repeat examination
Reassessment of this module will consist of a repeat examination. It is possible that there will also be a requirement to be reassessed in a coursework element.

The institute reserves the right to alter the nature and timings of assessment


Module Workload

Workload: Full Time
Workload Type Workload Description Hours Frequency Average Weekly Learner Workload
Lecture Class based instruction 2.0 Every Week 2.00
Lab Practical laboratory instruction 2.0 Every Week 2.00
Independent & Directed Learning (Non-contact) Self-directed study 3.0 Every Week 3.00
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
This module has no Part Time workload.

Module Resources

Recommended Book Resources
  • Gary Walsh 2014, Proteins: Biochemistry & Biotechnology, 2nd edition Ed., J. Wiley [ISBN: 9780470669853]
Supplementary Book Resources
  • Rodney J. Y. Ho 2013, Biotechnology and Biopharmaceuticals, Wiley Blackwell [ISBN: 9781118179796]
  • Mousa Adel Quarawi 2015, Introduction to Modern Pharmaceutical Biotechnology, CreateSpace Independent Publishing Platform [ISBN: 9781507718667]
This module does not have any article/paper resources
This module does not have any other resources

Module Delivered in

Programme Code Programme Semester Delivery
CR_SPHBI_8 Bachelor of Science (Honours) in Pharmaceutical Biotechnology 6 Mandatory
CR_SBIBI_7 Bachelor of Science in Applied Biosciences and Biotechnology 6 Mandatory

Cork Institute of Technology
Rossa Avenue, Bishopstown, Cork

Tel: 021-4326100     Fax: 021-4545343
Email: help@cit.edu.ie