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BIOT7003 - Industrial Biotechnology

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Title:Industrial Biotechnology
Long Title:Industrial Biotechnology
Module Code:BIOT7003
 
Duration:1 Semester
Credits: 5
NFQ Level:Intermediate
Field of Study: Biotechnology
Valid From: Semester 1 - 2017/18 ( September 2017 )
Module Delivered in 1 programme(s)
Module Coordinator: Brigid Lucey
Module Author: MARGARET LANE
Module Description: This module is designed to familiarise students with processes,layout and operation of biotechnology processes including traditional microbial and modern biopharmaceutical production processes.
Learning Outcomes
On successful completion of this module the learner will be able to:
LO1 Outline the principles of microbial fermentations and discuss selected industrial microbial processes.
LO2 Describe the requirements and operation of an upstream process for the production of a biopharmaceutical
LO3 Discuss a typical downstream process for a biopharmaceutical.
LO4 Identify the main considerations for ensuring the production of a pure, sterile and endotoxin free biopharmaceutical.
LO5 Provide an overview of the regulatory processes inherent in commercial biopharmaceutical production.
LO6 Demonstrate practical competence in selected biotechnology related techniques
Pre-requisite learning
Module Recommendations
This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named CIT module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
12841 BIOT6001 Introduction to Biotechnology
12930 BIOM6006 Microbial Diversity
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements

This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.

None
 

Module Content & Assessment

Indicative Content
Microbial fermentations
An overview of microbial fermentations. Description of primary and secondary metabolites and bioconversions.A description of selected economically important microbial fermentations
Upstream
Requirements and steps involved in the upstream process for a biopharmaceutical: Cell banks, media requirements ,bioreactor design, operating system.
Downstream
A general summary of the main requirements and stages in downstream processing: filtration, chromatography, virus removal ,endotoxin detection, clean rooms, and formulation.
Regulatory processes
An overview of the role of the FDA in ensuring the safe production of biotechnology related products. This section will also provide an overview of the clinical trial process.
Practical sessions
Laboratory sessions on selected areas of a biotechnology based production process. Including if possible Bioreactor operation, aseptic process, protein purification , environmental monitoring , endotoxin testing and site visits.
Assessment Breakdown%
Course Work40.00%
End of Module Formal Examination60.00%
Course Work
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Multiple Choice Questions Theory based assessment of lecture material 1,2 20.0 Week 7
Written Report Written reports and analysis of biotechnology based laboratory practical sessions . 1,2,3,4,5,6 20.0 Every Second Week
End of Module Formal Examination
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Formal Exam End-of-Semester Final Examination 1,2,3,5 60.0 End-of-Semester
Reassessment Requirement
Repeat examination
Reassessment of this module will consist of a repeat examination. It is possible that there will also be a requirement to be reassessed in a coursework element.

The institute reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Workload Description Hours Frequency Average Weekly Learner Workload
Lecture Class based instruction 2.0 Every Week 2.00
Lab Practical laboratory Instruction 2.0 Every Week 2.00
Independent & Directed Learning (Non-contact) Independent & directed learning 3.0 Every Week 3.00
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
This module has no Part Time workload.
 

Module Resources

Recommended Book Resources
  • Gary Walsh 2003, Biopharmaceuticals: Biochemistry and Biotechnology, 2nd Ed. [ISBN: 9780470843277]
Supplementary Book Resources
  • Baltz, Richard H.; Davies, Julian E.; Demain, Arnold L. 2010, Manual of Industrial Microbiology and Biotechnology, 3rd Ed., American Society for Microbiology (ASM) [ISBN: 978-1-55581-5]
  • Colin Ratledge and Bjorn Kristiansen 2006, Basic Biotechnology, 3rd Ed., Cambridge University Press; [ISBN: 9780521549585]
  • E. M. T. El-Mansi, C. F. A. Bryce, Arnold L. Demain, A.R. Allman 2007, Fermentation Microbiology and Biotechnology, 2nd Ed., Taylor and Frances group. LLC United States of America [ISBN: 9780849353345]
This module does not have any article/paper resources
This module does not have any other resources
 

Module Delivered in

Programme Code Programme Semester Delivery
CR_SBIBI_7 Bachelor of Science in Applied Biosciences and Biotechnology 5 Mandatory

Cork Institute of Technology
Rossa Avenue, Bishopstown, Cork

Tel: 021-4326100     Fax: 021-4545343
Email: help@cit.edu.ie