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BIOE7001 - Biomaterials

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Title:Biomaterials
Long Title:Biomaterials
Module Code:BIOE7001
 
Duration:1 Semester
Credits: 5
NFQ Level:Intermediate
Field of Study: Biomedical Engineering
Valid From: Semester 1 - 2016/17 ( September 2016 )
Module Delivered in 1 programme(s)
Module Coordinator: GER KELLY
Module Author: HUGH O DONNELL
Module Description: This subject gives the student a grounding in the application of biomaterials in medical devices. The student is introduced to the areas of polymeric, metal and ceramic biomaterials and the course then proceeds to deal with areas such as the in vivo performance and selection of biomaterials and also the testing of biomaterials and the interaction of biomaterials with tissues.
Learning Outcomes
On successful completion of this module the learner will be able to:
LO1 Discuss the interaction between living tissue and biomaterials.
LO2 Characterise biomaterials according to their biocompatibility and their in vivo chemical and physical stability.
LO3 Describe the use of biomaterials in medical devices.
LO4 Select suitable biomaterials for a particular design or application subject to appropriate design constraints whilst being mindful of economic, environmental and ethical issues.
LO5 Structure and prepare technical reports on the properties of biomaterials.
Pre-requisite learning
Module Recommendations
This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named CIT module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
No recommendations listed
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements

This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.

No requirements listed
Co-requisites
No Co Requisites listed
 

Module Content & Assessment

Indicative Content
Properties of Natural Materials
In vivo versus In vitro properties. Tissue constituents. Properties of Collagen and Elastin. Mechanical properties of bone, muscles, tendons, ligaments and cartilage. Viscoelastic models of material behaviour.
Polymers
Bio-polymers. Sterilisation issues. Resorbable polymers. Mechanical properties relevant to applications. Fabrics, threads and sutures.
Metals
Review of metals used in the biomedical industry. Evolution of metallic prostheses: Casting, mechanical forming, heat treatment, finishing, surface treatment and surface hardening. Shape memory alloys and their applications
Ceramics/Composites
Aluminium oxide, calcium phosphate, hydroxyapatite, glass-ceramics, carbons. Reactive ceramics. Composites used in the biomedical industry. Fabrication of composites. Mechanical properties. Dental fillings, porous implants, composite orthopaedic implants.
Corrosion and Degradation
Introduction (Corrosion). Chemistry of corrosion. Classification of corrosion. Relevance of corrosion to orthopaedic implants. Biodegradation of metals, polymers and ceramics. Calcification of biomaterials.
Host response
Local host response. Systemic and host response. Immunology and infection. Blood compatability, carcinogenicity.
Testing and Introduction of New Materials
The design process. Laboratory studies, material evaluation. Classes of devices. Equivalent materials. Clinical trials Clinical protocols. Release for general use. Standardisation
Materials Selection
Selection of materials for applications areas including: cardiovascular, neurological, dental, ophthalmologic, orthopaedic, drug delivery, sutures, dressings, artifical organs, maxillofacial and other soft tissue augmentation.
Assessment Breakdown%
Course Work45.00%
End of Module Formal Examination55.00%
Course Work
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Practical/Skills Evaluation Biomaterials Laboratory Reports 5 20.0 Every Second Week
Essay Materials selection assignment 4 10.0 Week 8
Short Answer Questions 1 Hour examination 2 15.0 Week 6
End of Module Formal Examination
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Formal Exam End-of-Semester Final Examination 1,2,3 55.0 End-of-Semester
Reassessment Requirement
Repeat examination
Reassessment of this module will consist of a repeat examination. It is possible that there will also be a requirement to be reassessed in a coursework element.

The institute reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Workload Description Hours Frequency Average Weekly Learner Workload
Lecture In Class Lecture 3.0 Every Week 3.00
Lab Biomaterials Labs 2.0 Every Second Week 1.00
Independent & Directed Learning (Non-contact) Self directed learning 3.0 Every Week 3.00
Total Hours 8.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
This module has no Part Time workload.
 

Module Resources

Recommended Book Resources
  • Brian W. Darvell, 2009, Materials Science for Dentistry, Ninth Edition, 9 Ed., Taylor & Francis London [ISBN: 9781439801055]
  • edited by Paul K. Chu and Xuanyong Liu 2008, Biomaterials fabrication and processing handbook, CRC Press/Taylor & Francis [ISBN: 9780849379734]
  • Park, J. 2007, Biomaterials: An Introduction, 3rd ed Ed., Springer USA [ISBN: 978-0387378794]
  • Ratner, B.D. 2004, Biomaterials Science: An Introduction to Materials in Medicine, 2nd Ed Ed., Academic Press USA [ISBN: 978-0125824637]
Supplementary Book Resources
  • Bhat, S.V. 2002, Biomaterials, Kluwer Academic Publisher The Netherlands [ISBN: 0792370589]
  • Lerouge, Sophie and Simmons, Anne 2012, Sterilisation of Biomaterials and Medical Devices, Woodhead Publishing [ISBN: 9781845699321]
This module does not have any article/paper resources
Other Resources
  • Software Package: Granta Design 2013, CES Selector-materials selection software
 

Module Delivered in

Programme Code Programme Semester Delivery
CR_EBIME_7 Bachelor of Engineering in Biomedical Engineering 5 Mandatory

Cork Institute of Technology
Rossa Avenue, Bishopstown, Cork

Tel: 021-4326100     Fax: 021-4545343
Email: help@cit.edu.ie